Metformin and exercise together 'may have adverse effect on diabetics'

Posted on 22 August 2011

Exercise may actually decrease the effectiveness of diabetes treatment metformin in those with the condition who may be paying for care, according to new research.

A study conducted at the University of Alberta revealed that while metformin worked to reduce glucose in the blood, better glucose control was observed after lunch on days where no exercising was undertaken.

Author Normand Boule believes that because both metformin and exercise work to lower glucose levels, the combination of both could trigger a counter regulatory response as the body acts to ensure levels do not drop too much.

"During exercise, glucagon concentrations increased in the blood (a hormone secreted by the pancreas that raises glucose levels) but when we combined exercise and metformin the glucagon levels were almost twice as elevated," he said.

In other news, Dr Alison Jeffery, from the Peninsula Medical School maintains that being overweight could cause diabetes.

Posted by Natalie Edwards



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