Four-in-one pill 'halves cardiovascular risk'

Posted on 26 May 2011

A combination pill, which incorporates four different drugs, has been seen halve the risk of stroke and heart disease, making it a potential treatment for people paying for care.

The once-a-day polypill contains aspirin and medications to reduce cholesterol and blood pressure and, according to the study published in PLoS One, halves the risk of the cardiovascular conditions.

However, side effects were seen to be more common than was forecasted, with around one in six people experiencing one, and approximately one in 20 discontinuing the treatment due to these problems.

This indicates the polypill would be best placed tackling high-risk cardiovascular patients.

Dr Ted Bianco, director of technology transfer at the Wellcome Trust, which provided the core funding for the study, said: "It is good news, indeed, to see the evidence base grow for the potential use of a new generation of combination products as a safe and affordable option in the battle against heart attack and stroke."

Meanwhile, research published in PLoS Medicine found that stroke survivors in inner-city London experienced poor long term outcomes with high levels of disability immediately following the stroke, and many patients experiencing moderate to severe disabilities for up to a decade after the event.

Posted by Natalie Edwards



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