Brain changes 'may be indicative of Alzheimer's'

Posted on 25 August 2011

A new study has identified changes in the brain of those who may be at risk of Alzheimer's, which could lead to treatment to help many paying for care.

In a paper published in journal Neurology, researchers used a brain imaging scan called proton MR spectroscopy to identify biochemical changes in the brain of people who may be at risk of Alzheimer's.

Participants also underwent PET scans to assess the levels of amyloid-beta deposits or plaques in the brain - a known characteristic of the neurodegenerative condition.

Jonathan M Schott, of University College London, said: "If we could identify people in whom the disease process has started but symptoms have not yet developed, we would have a potential window of opportunity for new treatments - as and when they become available - to prevent or delay the start of memory loss and cognitive decline."

Meanwhile, the development of Alzheimer's disease could be stopped by a 'road block' method which would obstruct transport pathways in brain cells, according to a paper published in the Proceedings of the National Academy of Sciences.

Posted by Nigel Murphy


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