New Alzheimer's, HIV treatment being developed

Posted on 26 June 2011

Scientists are developing a treatment which could delay the onset of Alzheimer's disease, helping those paying for long term care, and also prevent the sexual transmission of HIV.

A University of California Los Angeles team report that they have designed molecular inhibitors targeting specific proteins linked to Alzheimer's and HIV in order to prevent them forming amyloid fibres.

According to authors of the research, which is published in journal Nature, the study was a "first step" towards the development of structure-based drugs which are designed against amyloid diseases.

"Our results have opened up an avenue so that universities and industry can start creating therapeutics that could not have been produced 10 years ago," said research leader David Eisenberg.

Research published online in journal Neurology revealed that Alzheimer's disease could be better predicted thanks to a newly discovered biomarker.

Levels of protein soluble amyloid precursor protein beta were seen to be significantly higher in the spinal fluid of mild cognitive impairment patients who then went on to develop Alzheimer's.

Posted by Toby Mynott

 

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