Drug 'could fight Alzheimer's'

Posted on 01 June 2011

A new drug could be used to improve memory in Alzheimer's disease, research has indicated.

The oral administration of cystein protease inhibitor E64d was seen to improve the memory deficit in animal models, and reduce the build up of beta amyloid in the brain, according to the study published in the Journal of Alzheimer's Disease.

Increased levels of amyloid beta in the brain are believed to lead to increased memory loss and amyloid plaque, both of which are characteristic of Alzheimer's disease.

"The finding is especially exciting because E64d has previously been shown safe for use in humans, so we believe the compound has strong potential as a new therapy for Alzheimer's disease," said co-author Gregory Hook.

In other news, plant compounds could slow down Alzheimer's disease, according to research published in journal PLoS One.

It was discovered that beta-carboline alkaloids found in the family of plant compounds, could be used to stop or slow down the memory loss seen in the condition.

Posted by Nigel Murphy

 

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