Discovery of genes to enable arthritis screening?

Posted on 01 June 2011

Seven new genes have been associated with a certain type of arthritis, meaning genetic screening for the condition could in future be a possibility of at-risk groups, such as those with long term care plans.

Researchers from the University of Edinburgh believe that the genes could be associated with regulating the rate of renewal and repair of bones.

In Paget's disease, the development of the bone is impacted upon, meaning that sufferers can often have large and malformed bones.

"We have now identified seven genes that predispose people to Paget's. The effect of these is large, and together they considerably increase the risk of developing the condition," said study leader professor Stuart Ralston.

Meanwhile, a study published in the Journal of Bone and Joint Surgery found that patients with mild to moderate knee arthritis were particularly affected by depression.

The mental health condition appeared to worsen the symptoms of knee arthritis in older people.

Posted by Nigel Murphy



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